Acquired haemophilia A: an unusual postoperative complication

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[Acquired haemophilia].

Acquired haemophilia (AH) is a severe bleeding diathesis that affects both males and females. It is caused by suddenly appearing autoantibodies that interfere with coagulation factor VIII (FVIII) activity. Although some conditions such as autoimmune diseases, cancer and puerperium seem likely to induce AH, in more than half of the observed cases autoantibodies to FVIII are idiopathic. The clini...

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A Common Complication of Haemophilia

This paper describes and seeks to explain a clinical syndrome which occurs characteristically, but not exclusively, as a complication of haemophilia. The main features of the syndrome are the sudden onset of severe pain in the groin accompanied by marked flexion deformity at the hip, followed by a mass in the iliac fossa and femoral nerve palsy. Episodes of this sort have been reported in the l...

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Polyserositis: An Unusual Complication of Aluminum Phosphide Poisoning

  Background: Aluminum phosphide is the common cause of poisoning in adults in India, with a very high case fatality ratio. We studied five patients of aluminum phosphide poisoning with polyserositis. Methods: We enrolled all patients with aluminum phosphide poisoning presenting to emergency medical department, at a tertiary care hospital in northwestern India from January to July 2006. These p...

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Management of acquired haemophilia A.

Acquired haemophilia A (AHA) is caused by autoantibody inhibitors of coagulation factor VIII (FVIII : C). Recent onset of bleeds and isolated prolongation of the activated partial thromboplastin time (aPTT) are characteristic features of the disorder. Reduced FVIII : C activity and a detectable FVIII : C inhibitor in the Bethesda assay confirm the diagnosis. Patients should be referred to exper...

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ژورنال

عنوان ژورنال: BMJ Case Reports

سال: 2016

ISSN: 1757-790X

DOI: 10.1136/bcr-2016-217198